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kratom can cause many side effects, including tongue numbness, nausea,. in- utero effects of the crude ethanolic extract of the leaves of mitragyna speciose on neural tube powder formation in rats. effects of 15x kratom premium bali kratom powder extract. as mentioned earlier, consuming even just bali half a gram of a 15x kratom extract can result in full effects and benefits of the natural herb in the body. due to its high potency, it usually begins to show its effects in as short as 5- 15 minutes after consumption. for someone who wants a sedating pain- killing extract, a full- spectrum premium resin extract made bali from an indo or bali strain will prove very effective. while this is not always possible, it is a good idea to educate oneself on the natural effects of kratom and especially extracts to learn what alkaloids they contain at highest concentrations.